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Updated: Jun 29, 2025

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
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Published on: March 8, 2022

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通过招募KAT2AA,CircROR1提高了CCNE1的表达,以促进黑色素瘤的入侵和转移

Litong Sun1, Shizhen Bin1, Chenghui Huang1

  • 1Department of Oncology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Experimental dermatology
|April 3, 2024
PubMed
概括

循环RNA ROR1 (CircROR1) 通过通过KAT2A介导的基因素乙化来调节CCNE1表达,促进黑色素瘤的进展. 这一发现凸显了CircROR1作为黑色素瘤治疗的潜在治疗点.

关键词:
在CCNE1中,在CircROR1中,可以看到CircROR1.在KAT2A中,它是KAT2A侵袭和转移的发生.黑色素瘤是一种黑色素瘤.

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