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Updated: Jun 29, 2025

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通过计算研究揭示了二酶7A/8A抑制剂的选择性机制

Zhijian Wang1, Shizun Wang1, Hanxun Wang1

  • 1School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.

Physical chemistry chemical physics : PCCP
|April 3, 2024
PubMed
概括

研究了向化酶7A (PDE7A) 和化酶8A (PDE8A) 的选择性抑制剂. 关键氨基酸在它们的结合部位上的差异解释了这些抑制剂的选择性,这对于开发新疗法至关重要.

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