头骨底部骨髓炎 - 头骨的掠夺者
Lakshmi Krishnakumar1, Vishnu Vinayakumar1, B R Suchit Roy1
1Department of ENT, Government Medical College, Thiruvananthapuram, Kerala 695011 India.
概括
头骨基骨质炎是一种严重的骨感染,在COVID后越来越多地出现. 这项研究突出了临床特征,并主张为这种危险疾病制定统一的全球治疗指南.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
背景情况:
- 头骨基骨质炎 (SB0) 是一种严重的骨感染,患病率和死亡率高.
- 最近关于其日益增长的发病率的研究有限.
- 后COVID时代可能会在SB0中带来独特的挑战和变化.
研究的目的:
- 描述头骨基骨质炎的临床特征.
- 为了识别在COVID后期间SB0的变化.
- 鼓励制定统一的全球治疗政策.
主要方法:
- 140名被诊断患有SB0.0的患者进行了一项描述性研究.
- 数据收集包括半结构化proformas,HRCT骨发现,微生物学和组织病理学报告,ESR和House-Brackmann分级.
- 分析的重点是临床表现,致病生物,疾病程度和治疗反应.
主要成果:
- 最受影响的人口是61-70岁的男性,所有人都患有无法控制的糖尿病.
- 常见的表现包括夜间耳痛,耳道颗粒化和神经麻.
- Pseudomonas aeruginosa 和 Staphylococcus aureus 是最常见的细菌分离物; Candida albicans 是最常见的真菌病原体. 后COVID观察包括非典型的生物体,更广泛的疾病和改变的抗生素敏感性.
- 29.3%的人患有广泛的疾病; 43.75%的人对治疗有满意的反应. 冠状动脉疾病和脑血管事故是导致死亡的主要原因.
结论:
- 长期,培养敏感的抗生素治疗是骨骨质炎的支柱.
- 在COVID后的时期,SB0特征发生了变化,需要更新管理策略.
- 统一的全球治疗指南对于有效的患者管理至关重要.
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