早期全身性硬化症患者的胃节律失常:一个横截面研究
Daniela Seelmann1, María Paz Poblete1, Silvana Saavedra2
1Rheumatology Section, Medicine Department, Hospital Clínico de la Universidad de Chile, Santiago, Chile.
胃不运动性在早期系统性硬化症 (SSc) 中很常见. 电气胃摄影 (EGG) 可以帮助SSc患者早期诊断胃肠道 (GI) 问题.
科学领域:
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 在早期全身性硬化症 (SSc) 中,胃部的参与仍未得到充分研究.
- 胃肠道 (GI) 症状在SSc患者中很普遍.
研究的目的:
- 在早期的SSc. 调查胃节律失常.
- 评估胃节律失常,胃肠道症状和指甲折叠视频毛细血管镜 (NVC) 发现之间的关联.
主要方法:
- 一项涉及早期SSc患者的横截面研究.
- 患者完成了UCLA GIT 2.0问卷,接受了NVC和表面电胃镜 (EGG).
- 统计分析包括描述性统计和关联测试 (费舍尔,肯德尔·陶).
主要成果:
- 分析了29名早期SSc患者 (28名女性,平均年龄为48.7岁).
- 63%的人报告了中度至严重的胃肠道症状;28/29人有异常的EGG结果.
- 勃拉迪加斯是常见的 (70%) 并与社会功能受损相关,但没有发现与严重的胃肠道症状或NVC模式的相关性.
结论:
- 在早期的SSc中,胃不运动是常见的.
- EGG是一种灵敏,具有成本效益,非侵入性的工具,用于诊断肠道干预的SSc.
- 在这个队列中,胃肠道症状,NVC模式和EGG发现之间没有明确的关联.
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