头面部疾病和发育不良:分子,临床和管理视角
Sunday O Akintoye1, Akinyele O Adisa2, Chukwubuzor U Okwuosa3
1Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Bone reports
|April 3, 2024
概括
面骨疾病是复杂的,因为复杂的发展和各种表现. 本综述探讨了它们的分子,临床和管理复杂性,以更好地理解和治疗.
科学领域:
- 发展生物学 发展生物学
- 遗传学 是一个遗传学.
- 临床医学 临床医学
背景情况:
- 面骨疾病和形症是由复杂的胚胎发育引起的.
- 这些情况显示出显著的临床,病理和分子异质性,使分类复杂化.
- 虽然往往很少见,但它们会导致影响口面复合体的多样化表型.
研究的目的:
- 为了提供一个全面的概述的面骨疾病和骨质功能障碍.
- 从分子,临床和管理角度阐明复杂性.
- 突出需要一种多学科的方法来管理这些罕见的条件.
主要方法:
- 文献综述综合了关于面骨疾病的当前知识.
- 分子,临床和病理异质性的分析.
- 检查多学科的管理策略.
主要成果:
- 面发育的复杂性导致了广泛的骨疾病.
- 呈现的异质性需要量身定制的诊断和治疗方法.
- 有效的管理依赖于集成的,协作的专业努力.
结论:
- 了解分子和临床的复杂性对于诊断面位障碍至关重要.
- 协调,多学科的方法对于最佳的患者结果至关重要.
- 对潜在机制的进一步研究可以改善治疗干预措施.
相关概念视频
Overview of the Skull
4.5K
The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
4.5K
Sutures of the Skull
6.7K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.7K
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K


