在妊娠糖尿病中尿酸升高及其对妊娠结果的风险
Marwa Mostafa Ahmed1, Nagwa Eid Saad1, Shimaa Mohamed Abbas2
1Faculty of Medicine, Cairo University, Cairo, Egypt.
妊娠期糖尿病孕妇尿酸水平升高与孕妇和新生儿并发症风险增加有关. 这包括过早分娩,巨和剖腹产,突出显示尿酸监测的重要性.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 内分泌学 在内分泌学.
背景情况:
- 孕期糖尿病 (GDM) 的患病率在全球范围内正在增加.
- 以前的研究表明,GDM与尿酸水平升高之间存在相关性.
- 妊娠期高尿血与不良的孕产妇和新生儿结局有关.
研究的目的:
- 评估血清尿酸升高 (>5 mg/dl) 对患有GDM的女性怀孕结果的影响.
- 确定与高尿酸水平相关的特定风险,包括新生儿体重,呼吸困难和早产.
- 为了评估尿酸升高与母婴/新生儿重症监护室入院,膜早破,小水和剖腹产率之间的关联.
主要方法:
- 一项前性队列研究,涉及221名怀孕妇女在第三个三个月内患有GDM.
- 参与者来自开罗大学医院的产科/家庭医学门诊.
- 根据血清尿酸水平,女性被分为两组:≥5 mg/dl (n=121) 和≥5 mg/dl (n=100),并跟踪直到分娩.
主要成果:
- 在新生儿并发症,孕产妇并发症,早产,巨,新生儿重症监护室入院,膜前期破裂,小水和剖腹产率之间观察到有统计学意义的差异.
- 产前血清尿酸水平与不良妊娠结果有明显的关联.
结论:
- 血清尿酸升高 (>5 mg/dl) 是孕期糖尿病女性产妇和新生儿并发症的预测标志物.
- 高尿酸水平与早产,巨,新生儿重症监护室的入院,膜的过早破裂,小水和剖腹产的发生率增加有关.
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