在COVID-19中探索脊髓巨变和肺部参与之间的相关性:一项回顾性研究
Bharathi Priya Raju1, Balaji Selvaraj2, Sharmila Murugesan3
1Radiodiagnosis, Government Stanley Medical College and Hospital, Chennai, IND.
Cureus
|April 3, 2024
概括
这项研究发现,脏扩大和COVID-19患者的肺部参与之间存在弱,无意义的联系. 脏大小不是2019年冠状病毒病肺部并发症的可靠预测指标.
科学领域:
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 新冠病毒病2019 (COVID-19) 影响了呼吸道以外的多个器官系统.
- 脊髓大 (扩大脏) 是COVID-19的一个已知的肺外表现.
- 在COVID-19中大病和肺部参与之间的关系仍然不清楚.
研究的目的:
- 研究通过CT成像评估的脏大小与COVID-19患者肺部参与程度之间的相关性.
- 为了探索 COVID-19 严重性中大的潜在预后价值.
主要方法:
- 对1058名具有症状的COVID-19患者进行了回顾性横截面研究.
- 计算机断层扫描 (CT) 图像用于测量的大小和肺部卷入 (LI).
- 包括皮尔森相关性和线性回归在内的统计分析.
主要成果:
- 平均脏大小为9.49厘米;平均LI得分为0.272.
- 在脏大小和LI之间观察到边际正相关性 (r=0.0495).
- 的大小只解释了LI分数的0.2%的差异,这表明影响很小.
结论:
- 在COVID-19中大病和肺部参与之间存在统计学上非显著的相关性.
- 脏扩大可能表明系统性疾病,但不是肺损伤的强有力的独立预测因素.
- 需要进一步的研究,以了解脏参与COVID-19的全部影响.
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