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Updated: Jun 29, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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异环 (pyrazine) 碳胺Ru(ii) 复合物:与生物分子相互作用和细胞毒性的结构,实验和理论研究

Nokwanda Tsaulwayo1, Reinner O Omondi1, Paranthaman Vijayan1

  • 1School of Chemistry and Physics, University of KwaZulu-Natal Private Bag X01, Scottsville Pietermaritzburg 3209 South Africa ojwach@ukzn.ac.za.

RSC advances
|April 3, 2024
PubMed
概括

新的 (Ru1-Ru4) 复合物显示出有前途的抗癌活性. 化合物Ru1和Ru2有效地与DNA和蛋白质相互作用,对癌细胞表现出强烈的细胞毒性,在某些情况下甚至超过了西斯.

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