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Updated: Jun 15, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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基于双循环杂交连锁反应和G-quadruplex的纳米孔敏感化

Yanru Li1,2, Chunmiao Yu1,2, Yesheng Wang1,2

  • 1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China. binglingli@ciac.ac.cn.

Chemical communications (Cambridge, England)
|April 3, 2024
PubMed
概括

研究人员开发了一种核酸放大器,以提高固态纳米孔灵敏度. 这项创新解决了分辨率和噪声问题,增强了用于改进纳米孔传感应用的目标检测.

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相关概念视频

Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.