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通过改善HFD养小鼠的胰岛素信号通路,LRP1促进肝脏糖生成

Xingxian Guo1, Jiangxia Pu1, Ziqi Tang1

  • 1Centre for Lipid Research & Chongqing Key Laboratory of Metabolism on Lipid and Glucose, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Department of Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Animal models and experimental medicine
|April 3, 2024
PubMed
概括

与LDL受体相关的蛋白-1 (LRP1) 通过改善胰岛素信号传递来促进肝糖生成. 它的β链对于这一过程至关重要,为肝脏的胰岛素抵抗提供了潜在的治疗点.

关键词:
一个LRP1的LRP1葡萄糖生成 (glycogenesis) 是一种胰岛素耐药性是一种胰岛素耐药性.胰岛素的信号通路.

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