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嗅觉神经母细胞瘤的复发发病率

Katie Melder¹, Jess C Mace², Garret Choby³

¹Department of Otolaryngology-Head and Neck Surgery, Louisiana State University, New Orleans, Louisiana, USA.

International forum of allergy & rhinology

|April 3, 2024

概括

嗅觉神经母细胞瘤 (ONB) 的复发很常见. 局部或部复发显示出比内或远部复发更好的生存率,指导未来的监测.

科学领域:

在瘤学瘤学.
耳鼻喉科耳鼻喉科耳鼻喉科
神经外科神经外科

背景情况:

嗅觉神经母细胞瘤 (ONB) 改善了生存率,但复发率很高.
了解复发模式对于患者管理至关重要.

研究的目的:

为了分析ONB复发的预后.
调查复发副部位和生存结果之间的关联.

主要方法:

从九个学术中心对233个ONB病例 (2005-2021) 的回顾性审查.
使用描述性和时间到事件方法分析瘤特征,复发部位和生存数据.

主要成果:

30%的患者 (70/233) 经历了复发.
当地 (50%) 和部 (36%) 是常见的复发部位.
与高级T阶段,整体阶段和卡迪什分数相关的复发.
局部/部复发与较好的疾病特异性存活率 (DSS) 相比,内/远程复发.

结论:

复发性ONB病例因阶段和成像因素而有所不同.
复发部位显著影响DSS,独立于最初的瘤特征.
识别复发风险因素有助于患者咨询和监测计划.

关键词:

这是一个神经母细胞瘤.嗅觉神经母细胞瘤是一种神经母细胞瘤.复发性复发性复发性这是一种鼻性恶性瘤.头骨的基础骨的基础骨的基础

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