在高维自由能表面上进行无偏向的增强采样,使用深度生成模型

One of the challenges of using the second law of thermodynamics to determine if a process is spontaneous is that it requires measurements of the entropy change for the system and the entropy change for the surroundings. An alternative approach involving a new thermodynamic property defined in terms of system properties only was introduced in the late nineteenth century by American mathematician Josiah Willard Gibbs. This new property is called the Gibbs free energy (G) (or simply the free...

The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:

Biasing a Junction Field Effect Transistor (JFET) is crucial for setting operational parameters and ensuring efficient functioning in electronic circuits. JFETs are characterized by using a single carrier type in N-channel or P-channel configurations, where the channel is surrounded by PN junctions. These junctions are central to the device's ability to control current flow.
In an N-channel JFET, the structure consists of N-type material forming the channel on a P-type substrate, with the gate...

The directional derivative is a central concept in multivariable calculus that describes how a function changes at a given point when moving in a specified direction. This direction is represented by a unit vector, ensuring that only the orientation influences the rate of change. By varying the direction, different rates of change can be observed, demonstrating that the directional derivative depends strongly on the chosen direction.The directional derivative is computed using the gradient...

A parametric surface in three-dimensional space is defined through a vector-valued function\begin{equation*}\mathbf{r}(u, v) = x(u, v)\mathbf{i} + y(u, v)\mathbf{j} + z(u, v)\mathbf{k}\end{equation*}where u and v are parameters within a specified domain D in the uv-plane. The functions x(u, v), y(u, v), and z(u, v) define the coordinates of points on the surface. As u and v vary over D, the position vector r(u, v) traces a continuous surface in space. This parametric representation is essential...