糖尿病酸症的发作是否会影响儿科患者的甲状腺功能测试?
Gülhan Atakul1, Huseyin Anıl Korkmaz1,2, Ahmet Gönüllü1
1Pediatric Intensive Care Unit, Health Sciences University, Dr. Behçet Uz Children's Diseases and Surgery Training and Research Hospital, İzmir, Türkiye.
Journal of pediatric endocrinology & metabolism : JPEM
|April 3, 2024
概括
患有糖尿病酸症 (DKA) 的患者的甲状腺激素水平在严重发作期间可能不表明甲状腺疾病. 在这些急性代谢障碍病例中,常规甲状腺功能测试可能是不必要的.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 糖尿病酸性酸症 (DKA) 是糖尿病的一种严重的代谢并发症.
- 在急性疾病期间,甲状腺激素水平可能会发生变化,这种情况被称为甲状腺疾病综合征.
研究的目的:
- 在DKA期间和之后调查甲状腺激素水平的变化.
- 为了确定在严重的DKA发作期间是否需要甲状腺功能测试.
主要方法:
- 包括85名被诊断患有DKA的患者.
- 在入院和1个月后进行甲状腺功能测试 (TFT) 的比较.
- 根据DKA的严重程度和甲状腺状况 (euthyroid与euthyroid病症综合征) 分类患者.
主要成果:
- 观察到与入院相比,DKA后1个月的TFT显著增加.
- 在轻度/中度和重度DKA组之间没有发现显著的TFT差异.
- 发现甲状腺疾病综合征和甲状腺疾病组之间的TSH水平存在差异,这与现有的文献相反.
- 发现低FT4和高HbA1c之间存在微弱的相关性.
结论:
- 在严重的DKA期间,甲状腺激素水平可能不准确地反映甲状腺疾病.
- 在患有严重DKA的患者中,例行甲状腺功能测试可能是不必要的.
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