在怀孕和产后期间治疗缺血性中风的急性再通道化疗法
Anna Richardt1, Karoliina Aarnio2, Aino Korhonen2
1Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. anna.richardt@helsinki.fi.
Journal of neurology
|April 3, 2024
概括
与对照组相比,对母亲缺血性中风 (IS) 的重新化疗法显示出罕见的并发症和类似的结果. 孕产妇IS患者应考虑在符合条件时接受这种治疗.
科学领域:
- 神经学 神经学
- 产科 产科 产科 产科 产科
- 心血管医学 心血管医学
背景情况:
- 对于母亲缺血性中风 (IS) 的再通道化治疗的安全性和有效性尚未得到充分证实.
- 有限的数据存在于并发症和输静脉血栓溶解 (IVT) 和内血管血栓切除在怀孕或产后的个体的结果.
研究的目的:
- 评估母亲IS的再通道化疗法的并发症和结果.
- 为了比较IVT治疗的孕产妇IS患者与对照者的结果.
主要方法:
- 在芬兰 (1987-2016) 进行全国性队列研究,使用链接的国家医疗保健登记册.
- 从患者记录中对诊断的回顾性验证.
- 进行IVT治疗的孕产妇IS患者与年轻女性对照组进行了比较,这些对照组患有与妊娠无关的IS.
主要成果:
- 12.4%的母亲IS病例接受了再通道治疗.
- 接受IVT治疗的母亲IS患者表现出更频繁的早期和主要的神经改善 (NIHSS).
- 三个月后的良好功能结果是相似的;然而,长期的良好功能结果在接受再通道治疗的患者中不太常见.
结论:
- 对于母亲IS的再通道化疗法,罕见的并发症和类似对照结果.
- 孕产妇的IS不应该被排除在回治疗之外,如果患者有其他资格.
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