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体重状态类别之间的童年过渡:来自英国千年队列研究的证据
Olu Onyimadu1, Nerys M Astbury2, Felix Achana2
1Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK. olu.onyimadu@phc.ox.ac.uk.
PharmacoEconomics
|April 3, 2024
概括
儿童体重状况的转变随着时间的推移而变化不稳定,年幼的孩子更有可能从健康体重转变为超重. 这些模式因年龄和人口统计学因素而异,为目标干预提供了信息.
科学领域:
- 儿科卫生保健 儿科卫生保健
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 估计儿童超重转型风险对于成本效益分析至关重要.
- 现有的估计缺乏国家代表性,并依赖于未经验证的假设.
研究的目的:
- 估计儿童体重状态转变概率和危险比率.
- 验证时间均过渡的假设.
- 考虑复杂的调查设计,以确保国家代表性.
- 探索人口统计学对体重状况变化的影响.
主要方法:
- 多州过渡建模应用于英国千年队列研究 (MCS) 数据 (3-17岁).
- 包含复杂的调查设计特征 (重量,刀复制品).
- 使用专门的MCS数据集验证的模型.
- 分析过渡期与儿童,母亲和社会人口统计学因素之间的关系.
主要成果:
- 年龄较小的儿童 (3-7岁) 与年龄较大的儿童相比,每年从健康体重转变为超重的概率更高.
- 体重状况的转变,特别是不健康体重的解决,是年龄相关的.
- 过渡危险根据儿童,母亲和社会人口统计学特征显著变化.
结论:
- 在英国儿童群体中开发了对体重状况转变的可靠估计.
- 证明了非时间均的过渡率,反驳了先前的假设.
- 突出了过渡危险的显著年龄和子组变化,支持为儿童体重管理干预措施量身定制的成本效益分析.
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