大脑组织的梯度:从方法开发到用户社区的顺航行
Jessica Royer1, Casey Paquola2, Sofie L Valk3
1Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada. jessica.royer@mail.mcgill.ca.
Neuroinformatics
|April 3, 2024
概括
大脑成像梯度显示大脑的大规模组织. 可访问的方法,数据共享和开源软件推动了社区对这些强大的神经科学工具的兴趣.
科学领域:
- 神经科学是一个神经科学.
- 神经成像是一种神经成像.
- 计算神经科学是一种神经科学.
背景情况:
- 多模式神经成像为人脑结构和功能提供了体内洞察力.
- 大脑梯度提供了一个框架,在多个尺度上统一大脑组织的原则.
- 最近的进展使得对大脑结构和功能的空间趋势之间的相互作用的研究成为可能.
研究的目的:
- 审查关于大脑梯度框架的当前文献.
- 突出实用步骤如何增加可访问性和渐变方法的采用.
- 论证社区建设的努力催化了对大脑梯度的兴趣.
主要方法:
- 关于大脑梯度框架的当前文献的综述.
- 重点是数据共享,开源软件开发和研讨会.
- 分析促使社区对梯度方法产生热情的因素.
主要成果:
- 实用性的步骤将渐变方法推向了神经科学研究的最前沿.
- 对渐变方法的兴趣在很大程度上是由社区驱动的倡议催化.
- 对大脑梯度日益增长的兴奋是神经信息学中成功建立社区的典范.
结论:
- 建立包容性社区的协调努力推动了对大脑梯度的兴奋.
- 大脑梯度作为未来神经信息学创新的一个模型.
- 持续进步需要解决理论改进,方法创新和现实世界翻译方面的挑战.
相关概念视频
01:20Anatomy of the Brain: Major Regions
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
01:13Functional Brain Systems: Reticular Formation
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
01:30Organization of the Brain
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...