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Updated: Jun 29, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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一个LATS2和ALKBH5的正反循环支持它们的致癌作用

Lei Cao1, Ruohui Han2, Yingying Zhao1

  • 1State Key Laboratory of Experimental Hematology, the Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Key Laboratory of Medical Epigenetics, Department of Cell Biology, Tianjin Medical University, Qixiangtai Road 22, Tianjin 300070, China.

Cell reports
|April 3, 2024
PubMed
概括

细胞密度影响了ALKBH5在质母细胞瘤中的N(6) - 甲基亚丁素 (m6A) 调节. LATS2酸化ALKBH5,形成一个反循环,促进瘤生长,并建议新的抗癌策略.

关键词:
CP: 癌症 癌症 癌症

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