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相关实验视频

Updated: Jun 29, 2025

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens
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Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

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样本宽度会影响血管组织完整性,用于体外表征.

Marta Alloisio1, Joey J M Wolffs2, T Christian Gasser1

  • 1Material and Structural Mechanics, Department of Engineering Mechanics, KTH Royal Institute of Technology, Sweden.

Journal of the mechanical behavior of biomedical materials
|April 3, 2024
PubMed
概括

准备精细组织样本可以改变机械性能. 较窄的轴向样本 (4毫米) 显示血管壁刚度降低 (~40%),表明切割创伤会影响结果.

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Corrigendum to "Fracture of porcine aorta-Part 1: symconCT fracture testing and DIC" [Acta Biomaterialia 2023, 167, 147-157].

Acta biomaterialia·2025

科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 心血管研究研究心血管研究

背景情况:

  • 组织机械性质的体外表征对于了解疾病和开发治疗方法至关重要.
  • 样本准备方法可以无意中改变本地组织生物力学.
  • 猪大动脉作为人类动脉组织研究的相关模型.

研究的目的:

  • 调查样品制备,特别是条纹宽度对猪大动脉组织机械性质的影响.
  • 为了确定样本准备期间的切割是否引入了影响单轴拉伸试验结果的工件.
  • 为了区分对周边负荷和轴负荷样本的影响.

主要方法:

  • 准备了猪大动脉壁的矩形样本,宽度不同 (16毫米,8毫米,4毫米),使用与负载方向平行的切口.
  • 沿着大动脉的圆周和轴向应用了单轴拉伸负荷.
  • 用有限元分析 (FEA) 来建模纤维滑动和样本行为.

主要成果:

  • 周围装载的标本无论宽度如何都表现出一致的机械性能.
  • 轴负载样本显示,在最窄的 (4毫米) 条带中,血管壁硬度降低了约40%.
  • 标本宽度显著影响了交叉负载的延伸,纤维滑动有助于在细小的标本中软化.
关键词:
纤维的滑动 纤维的滑动有限元素模型的模型.机械创伤是一种机械创伤.尺寸效应 尺寸效应 尺寸效应 尺寸效应拉力测试 拉力测试 拉力测试

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相关实验视频

Last Updated: Jun 29, 2025

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens
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Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

Published on: January 24, 2016

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结论:

  • 切割与原纤维方向直角的样本会诱导机械创伤,削弱纤细的拉力样本.
  • 制备狭窄的,轴负载的大动脉样本,使得本土机械性质的准确确定受到损害.
  • 仔细考虑样本的几何和准备对于可靠的血管组织体外生物力学测试至关重要.