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Updated: Jun 29, 2025

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
09:33

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling

Published on: March 20, 2018

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一项试点研究,探讨由[a]pyrene引起的时间和剂量依赖的DNA损伤和染色体不稳定性,在两种尿细胞类型中进行

Jonas Wohlfahrt1, Nisha Verma1, Rasha Alsaleh1

  • 1Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestr. 9-11, Erlangen 91054, Germany.

Mutation research
|April 3, 2024
PubMed
概括

多环芳 (PAH),特别是 (B[a]P),可以导致DNA损伤,增加尿细胞癌症的风险. 与T24癌细胞相比,PUBEC细胞对B[a]P诱导的DNA损伤的敏感性更高.

关键词:
[a]二烯是一种基二烯.致癌性 致癌性 致癌性基因毒性 基因毒性主要的泌尿器膀细胞.尿路细胞癌是什么意思

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