通过粘膜给药的巴比他和芬尼托因溶液诱导了胡须龙 (Pogona vitticeps) 的安乐死
Amanda D Wong1,2, Danielle M Lang1,2, Jacob P Dalen1
1Wildlife Epidemiology Laboratory, College of Veterinary Medicine, University of Illinois, Urbana, IL.
American journal of veterinary research
|April 3, 2024
概括
超粘膜安乐死溶液在六小时内有效地诱导了胡须龙的安乐死. 然而,口腔刺激和潜在的粘膜损伤需要用止痛药或麻醉药进行预治疗.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 类学 类学 类学 类学
- 药理学 药理学是指药理学的学科.
背景情况:
- 爬行动物的安乐死协议比哺乳动物的安乐死协议少.
- 通过菌体给药为爬行动物药物输送提供了潜在的替代途径.
研究的目的:
- 为了评估一个跨粘膜安乐死溶液在胡须龙 (Pogona vitticeps) 的疗效.
- 评估安乐死诱导的时间进程,并确定任何不良影响.
主要方法:
- 六只长胡须的龙通过粘膜接受了两剂丁巴比塔尔和丁溶液.
- 监测生理参数,反射和对刺激的反应,直到死亡确认.
- 尸体遗传学检查了口腔和胃肠组织的粘膜损伤.
主要成果:
- 死亡的中位时间为300分钟;呼吸停止和失去深度疼痛反应的中位时间为30分钟.
- 在66.7%的中出现了口腔刺激症状,其中16.7%的膜.
- 副作用包括两只的全身.
结论:
- 超粘膜安乐死溶液在6小时内在胡须龙中实现了临床安乐死.
- 由于潜在的口腔刺激和痛苦,建议使用止痛药/麻醉药进行前期治疗.
- 这种方法需要仔细考虑客户拥有的动物.
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