临床阶段的Nrf2激活剂通过铁-甲基因轴抑制骨质细胞分化

Yimin Dong1, Honglei Kang1, Renpeng Peng1

  • 1Department of Orthopaedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Cell metabolism
|April 3, 2024
PubMed
概括

比托珀丁是一种新型Nrf2激活剂,通过抑制骨质细胞分化和骨质损失来治疗骨质疏松症. 这种糖氨酸吸收抑制剂的副作用比现有治疗方法少,揭示了一个新的Nrf2-铁-甲尼丁通路.

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