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Updated: Apr 11, 2026

An Innovative Method for Exosome Quantification and Size Measurement
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An Innovative Method for Exosome Quantification and Size Measurement

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使用DNA三脚体对外体的尺寸选择捕获

Ryosuke Iinuma1,2, Xiaoxia Chen3, Takeya Masubuchi1,4

  • 1Graduate School of Frontier Science, The University of Tokyo, Chiba 277-8562, Japan.

Journal of the American Chemical Society
|April 3, 2024
PubMed
概括

研究人员开发了一种DNA原形三脚式纳米装置,用于有效净化细胞外囊泡 (EV). 这种方法通过同时根据大小和生物标志物进行选择,简化了从小样本中分离EV.

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相关概念视频

Size-Exclusion Chromatography01:08

Size-Exclusion Chromatography

In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
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