意识到被处方的抗高血压药物和心血管结果
Yuta Suzuki1,2, Hidehiro Kaneko1,3, Akira Okada4
1Department of Cardiovascular Medicine, The University of Tokyo.
概括
没有意识到正在服用血压药物的患者面临更高的心血管疾病 (CVD) 风险,包括心脏病发作和中风. 这凸显了患者意识对于管理高血压和预防严重心脏事件的重要性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 高血压是心血管疾病 (CVD) 的主要原因之一.
- 缺乏对高血压的认识有助于血压控制不良和心血管疾病风险升高.
- 全国范围的关于无意识个体及其临床结果的数据有限.
研究的目的:
- 调查抗高血压药物处方不知情与患心血管疾病的风险之间的关联.
- 为了澄清高血压治疗的个体中缺乏意识的临床影响.
主要方法:
- 使用JMDC索赔数据库进行回顾性队列研究.
- 包括313,715名服用抗高血压药物的高血压患者.
- 主要终点:心肌梗塞,胸痛,中风,心力衰竭和心房动的组合.
主要成果:
- 6.2%的人不知道他们的抗高血压药物处方.
- 没有意识与复合心血管疾病事件的更高风险有关 (HRs从1.15到1.36不等).
- 这种关联在敏感性分析中持续存在,包括那些排除痴呆症患者的敏感性分析.
结论:
- 评估患者对抗高血压药物的认识对于识别患有心血管疾病事件高风险的个体至关重要.
- 提高患者意识可能是高血压管理和心血管疾病预防的关键策略.
相关概念视频
Errors occurring during blood pressure monitoring
720
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
720
Factors affecting Blood pressure
3.2K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Physiological Factors:
3.2K
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
424
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
424
Antianginal Drugs: Nitrates and β-Blockers
580
In cardiovascular health, antianginal drugs combat angina pectoris — a condition marked by chest pain owing to diminished blood flow to the heart.
Organic nitrates, such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
Organic nitrates, such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
580
Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers
797
β-receptor blockers significantly impact the cardiovascular system by counteracting catecholamine-induced sympathetic responses. These medications decrease heart rate, contractility, and cardiac output, potentially leading to cardiac depression, life-threatening bradycardia, and death. Therapeutically, β-blockers function as mild antihypertensives and are utilized in treating angina pectoris and cardiac arrhythmias. However, nonselective β-blockers inhibit β2-receptors in...
797
Hypertension and Regulation of Blood Pressure
2.1K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.1K


