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药物制品配方和填充/完成制造工艺 基于AAV的基因组药物的考虑因素

Madhura Som1, Benson Gikanga1, Varna Kanapuram1

  • 1Sangamo Therapeutics, 7000 Marina Boulevard, Brisbane, CA 94005, United States.

Journal of pharmaceutical sciences
|April 3, 2024
PubMed
概括

基因相关病毒 (AAV) 对于基因疗法至关重要,但面临着稳定性挑战. 本审查审查了配方和工艺开发,以确保AAV药物产品在整个生命周期中的质量.

关键词:
AAV 稳定性 AAV 稳定性腺相关病毒 (AAV)关键的质量属性是关键的质量属性.药物产品的过程 药物产品的过程药物物质过程 药物物质过程配方和药物产品的制剂基因治疗是一种基因疗法.基因组医学是一种基因组医学.管理的途径.

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