在动态通风CT上,右主肺动脉延伸度及其与呼吸功能相关性
Tatsuya Oki1, Yukihiro Nagatani2, Shota Ishida3
1Department of Radiology, Shiga University of Medical Science, Seta-Tsukinowa-Cho, Otsu, Shiga, 520-2192, Japan.
European radiology experimental
|April 3, 2024
概括
慢性阻塞性肺病 (COPD) 患者的呼气障碍与主要肺动脉延展能力 (MPAD) 的降低有关. 动态通风CT评估MPAD提供了洞察力肺高血压的发病因子.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 心血管成像 - 心血管成像
背景情况:
- 肺高血压与主要肺动脉 (MPA) 截面区域 (CSA) 的变化有关,反映了其延展性.
- 动态通风计算断层扫描 (DVCT) 允许测量呼吸期间基于心跳的MPA CSA变化.
- 长期阻塞性肺病 (COPD) 患者中,MPA阻塞性 (MPAD) 和呼吸功能之间的关系需要进一步研究,特别是在慢性阻塞性肺病 (COPD) 患者中.
研究的目的:
- 调查主要肺动脉张张能力 (MPAD) 和呼吸功能之间的关系.
- 探索基于心跳的MPA横截面积 (CSA) 变化如何与螺旋计,平均肺密度 (MLD) 和患者特征相关.
- 通过使用DVCT分析所有呼吸各个阶段的MPAD.
主要方法:
- 从37名肺癌患者 (18名COPD患者,19名没有COPD患者) 的DVCT数据的回顾性分析.
- 使用离散里埃转换将MPA-CSA分离为呼吸和心跳波.
- 在吸入和呼出过程中计算CSA变化 (CSAC) 和CSA变化比率 (CSACR),然后进行斯皮尔曼等级相关性分析.
主要成果:
- 在非COPD患者和所有病例中,呼出CSACR与百分比剩余肺体积 (%RV) 和RV/总肺容量相反相关.
- 在COPD患者中,吸入CSAC与MLDmax和MLD变化率相关.
- 慢性肺炎患者显示出呼气CSAC/CSACR和吸入CSAC之间的相关性.
结论:
- 在呼吸不足的患者中观察到呼吸过程中右侧MPAD的减少.
- 患有呼吸障碍的COPD患者在吸入和呼气时表现出减少的右侧MPAD.
- 呼吸障碍是导致COPD患者肺高血压的一个因素.
- 在DVCT上对MPAD的评估可以作为评估由于肺部疾病和/或缺氧引起的肺高血压的非侵入性工具.
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