选择一个LMIC土著人口的出生体重标准:一个前性比较研究
Lut Geerts1, Lucy T Brink1, Hein J Odendaal1
1Department of Obstetrics and Gynecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Parow, South Africa.
概括
国际成长21世纪标准最能反映出南非健康妇女出生体重的分布. 体重,BMI,均值和妊娠年龄等母亲因素显著影响婴儿出生体重.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 公共卫生 公共卫生
背景情况:
- 出生体重 (BW) 是新生儿健康和发育的关键指标.
- 准确的BW引用对于监测胎儿生长至关重要,特别是在多样化的群体中.
- 现有的BW标准可能无法准确地反映特定种族或社会经济群体的增长模式.
研究的目的:
- 为了比较健康南非妇女的低风险单子妊娠的出生体重分布和百分位数类别,与四个已建立的BW参考.
- 为了确定影响该人口出生体重的生理因素.
- 为了确定这个群体最合适的BW参考标准.
主要方法:
- 一个潜在的跨国队列的辅助研究,涉及739名健康的南非妇女,没有并发症的怀孕.
- 与INTERGROWTH-21st,定制的Mickolajczyk,胎儿医学基金会和修订的芬顿参考资料相比,BW中位数和百分比 (
P90,95,97) 的比较. - 多重回归分析以确定影响BW的孕产妇和妊娠因素,包括孕产妇体重,BMI,平价值和妊娠年龄.
主要成果:
- 国际成长21st标准与观察到的BW分布和百分位数类别最接近.
- 低于预期的BW与男婴,较年轻的孕产妇年龄,较矮的孕产妇身高,较低的孕产妇BMI,较低的平行率和较低的孕期有关.
- 产妇体重,BMI,平价值和妊娠年龄是实际BW的重要决定因素.
结论:
- 建议使用INTERGROWTH-21st标准作为评估南非健康,低风险单胎妊娠中出生体重分布的最合适的参考标准.
- 母亲生理学变量在决定胎儿生长和出生体重方面起着至关重要的作用.
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