怀孕期间非功能性垂体腺瘤的医疗和手术方法
Ach Taieb1, Nassim Ben Haj Slama1, Emna Mraihi1
1Endocrinology, University Hospital of Farhat Hached, Sousse, TUN.
Cureus
|April 4, 2024
概括
在怀孕期间,有症状的非功能性垂体腺瘤 (NFPA) 是罕见的. 在一名患有NFPA的孕妇患者中,卡伯戈林治疗稳定了腺瘤,允许继续怀孕,并改善了临床状况.
科学领域:
- 内分泌学 在内分泌学.
- 神经瘤学神经瘤学
- 生殖医学 生殖医学
背景情况:
- 非功能性垂体腺瘤 (NFPA) 通常在老年人中被诊断出来,并且在怀孕期间很少出现症状.
- 怀孕期间有症状的NFPA非常罕见,记录的病例有限.
研究的目的:
- 在怀孕期间报告一种罕见的症状性垂体腺瘤病例.
- 评估卡伯戈林治疗在怀孕期间管理大垂体腺瘤的疗效和安全性.
主要方法:
- 一名39岁的孕妇患有大垂体腺瘤.
- 眼科检查显示视力受损.
- 在获得患者同意后,开始高剂量卡贝戈林 (每周3毫克) 治疗.
主要成果:
- 患者成功完成了怀孕,通过阴道分娩出了一个健康的婴儿.
- 卡伯戈林治疗稳定了垂体腺瘤的大小,改善了患者的临床状况.
- 产后手术显示下垂体腺瘤同时表达ACTH,PRL和GH; 然而,排除了荷尔蒙过分分泌.
- 确定了术后缺陷 (皮质otropic 和 somatotropic),需要替代治疗.
结论:
- 卡伯戈林是怀孕期间症状性垂体腺瘤的潜在治疗选择,可使怀孕继续并改善母亲的结果.
- 这一案例突出了第三例在怀孕期间使用卡贝戈林来治疗垂体腺瘤的情况.
- 对于残留腺瘤和激素缺陷的手术后,长期监测和替代治疗至关重要.
相关概念视频
01:27Hormones of the Pituitary Gland
6.6K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
6.6K
01:28Angle Closure Glaucoma: Treatment
485
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
485