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感染性休克儿童的营养摄入量:一项回顾性单中心研究
Angela H P Kirk1, Chengsi Ong2, Judith J-M Wong3,4
1Division of Nursing, Children's Intensive Care Unit, KK Women's and Children's Hospital, Singapore, Singapore.
Journal of pediatric intensive care
|April 4, 2024
概括
在患有严重败血症或败血症休克的儿童中,肠道营养 (EN) 显著改善了结果,降低了死亡率并增加了空日. 早期的EN启动显示了最大的益处,突出了其在儿科重症监护中的重要性.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 儿童营养学 儿童营养学
- 传染性疾病 传染性疾病
背景情况:
- 对于儿科严重败血症和败血症休克的营养实践还没有得到很好的定义.
- 了解营养摄入量对于改善重症儿童的临床结果至关重要.
研究的目的:
- 描述严重败血症或败血性休克儿童的营养摄入量.
- 调查营养摄入量与临床结果之间的关联,包括死亡率和逗留时间.
主要方法:
- 在2009年至2016年期间接受PICU治疗的74名儿科患者进行了回顾性研究,他们患有严重的败血症或败血性休克.
- 营养路径的分析 (肠道营养[EN],肠道营养[PN],静脉注射液体),能量和蛋白质摄入的充足性.
- 临床结果的评估:死亡率,无呼吸器日 (VFD) 和无PICU日 (IFD).
主要成果:
- 只有10.8%和5.4%的患者获得了足够的能量和蛋白质摄入量.
- 与没有接受EN的患者相比,接受EN (早期或晚期) 的患者的死亡率明显降低,VFD更多,IFD更多.
- 不足够的卡路里和蛋白质摄入量与死亡率没有直接关联.
结论:
- 在患有严重败血症或败血症休克的儿童中,肠道营养与改善的临床结果有关.
- 早期启动EN似乎特别有益.
- 需要进一步的前性研究来确定最佳的EN时间和目标.
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