自闭症谱系障碍和早期精神病:从神经发育角度进行叙事审查
Silvia Guerrera1, Maria Pontillo1, Fabrizia Chieppa1
1Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Frontiers in psychiatry
|April 4, 2024
概括
自闭症谱系障碍 (ASD) 和精神分裂谱系障碍 (SSD) 分享神经发育起源和重叠症状,挑战传统的诊断分离. 需要进一步的研究来了解它们的临床过程,并确定向治疗.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
背景情况:
- 自闭症谱系障碍 (ASD) 和精神分裂谱系障碍 (SSD) 是不同的神经发育障碍 (NDD) 根据DSM-5.
- 最近的观点表明神经发育连续性,突出了ASD和SSD之间的共同起源和症状重叠.
- 根据新兴的研究,传统的诊断界限越来越多地被重新评估.
研究的目的:
- 更新关于临床症状过程和ASD和SSD之间的重叠的当前知识.
- 探索神经发育的角度,了解ASD和SSD之间的关系.
- 识别科学文献中关于长期疗程和预后标志物的空白.
主要方法:
- 2010年1月至2023年6月期间发表的科学文献的叙事综述.
- 包括符合审查标准的五项研究.
- 分析的重点是临床症状,神经发育方面和预后标志物.
主要成果:
- 所有包括的研究都表明ASD和SSD的全球损害.
- 神经发育的观点是两个关于ASD和SSD的研究的重点.
- 三项研究强调了显著的症状重叠,包括ASD和SSD之间的负面,无组织和积极的症状.
结论:
- 从神经发育的角度来看,在研究检查临床症状的过程和ASD和SSD之间的重叠方面存在着显著的差距.
- 这些发现强调需要进行纵向研究,以确定风险标志物,并为这些疾病开发量身定制的治疗方法.
- 对神经发育连续性的更深入的理解可能会为未来的诊断和治疗方法提供信息.
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