老年人认知功能与身体组成之间的关联:来自NHANES (1999-2002) 的数据
Lianghua Chen1, Liling Zou2, Jingwen Chen1
1Department of Rehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong Province, China.
Frontiers in aging neuroscience
|April 4, 2024
概括
较低的骨矿物质密度与老年人的认知能力下降有关,特别是60-80岁的女性. 其他身体成分测量没有显示出认知相关性.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 认知功能自然会随着年龄的增长而下降.
- 身体组成的变化,包括骨密度,发生在老年人中.
- 了解身体组成和认知之间的联系对于健康的衰老至关重要.
研究的目的:
- 检查各种身体组成指标与老年人认知功能之间的关联.
- 为了确定可能影响老年人群认知健康的特定身体组成因素.
主要方法:
- 利用了来自1999-2002年国家健康和营养检查调查 (NHANES) 的2080名老年人 (>60岁) 的数据.
- 采用后勤回归来分析认知功能和身体组成变量 (骨矿物质密度,脂肪质量等) 之间的关联. ) 的情况.
- 根据性别和年龄组进行了分层分析,以探索差异效应.
主要成果:
- 总骨矿物质密度与认知功能显著相关 (p<0.01).
- 这种关联在女性 (p<0.01) 中是显著的,但在男性 (p=0.081) 中是显著的.
- 骨矿物质密度与60-70岁 (p=0.019) 和70-80岁 (p=0.022),但不超过80岁的成年人的认知功能相关.
结论:
- 总骨矿物质密度下降与老年人的认知能力下降有关,特别是女性和60-80岁的人.
- 其他身体组成指标 (脂肪量,瘦肉量) 与认知功能之间没有发现显著的相关性.
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