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Updated: Jun 29, 2025

Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes
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Published on: November 1, 2011

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Rev1过度表达通过增加突变发生加速N-甲基-N-尿素 (MNU) 诱导的胸膜淋巴瘤

Megumi Sasatani1, Yang Xi1,2, Kazuhiro Daino3

  • 1Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.

Cancer science
|April 4, 2024
PubMed
概括

Rev1的过度表达加速了突变发生,并通过增强遗传不稳定性和缩短DNA损伤后的疾病潜伏时间,增加了小鼠的胸腺淋巴瘤发病率.

关键词:
在DNA转化合成过程中.突变发生的突变发生.甲状腺淋巴瘤 (thymic lymphoma) 是一种淋巴瘤.瘤发生的起源整个exome测序的测序

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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development11:02

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