在休活动的骑自行车者中,高体积耐力运动后的凝血活动和血栓形成风险
Blake E G Collins1, Michael Kingsley1,2, Brett A Gordon1
1Holsworth Research Initiative, La Trobe Rural Health School, La Trobe University, Bendigo, Victoria, Australia.
Journal of applied physiology (Bethesda, Md. : 1985)
|April 4, 2024
概括
高体积的耐力运动可能会在休骑自行车者中引起心脏压力. 然而,凝血标记表明,当保持适当的水分和休息时,血栓形成风险不会增加.
科学领域:
- 运动生理学 运动生理学
- 心血管生理学心血管生理学
- 血液静止 血液静止 血液静止
背景情况:
- 身体活动通常对健康有益,但强烈的耐力运动可能会带来风险.
- 急性高体积耐力运动会导致心脏压力和高凝血.
- 了解这些影响对于进行长时间体力活动的休运动员至关重要.
研究的目的:
- 研究高体积耐力运动对凝血和血栓活动的影响.
- 在休运动员中长时间骑自行车后评估心脏压力标志物.
- 为了确定运动诱导的变化是否会增加血栓形成的风险.
主要方法:
- 34名休骑自行车者进行了4.8小时的自行车运动.
- 血液样本是在运动前,运动后立即和运动后24/48小时收集的.
- 分析的生物标志物包括心脏热素 (cTn),C反应蛋白 (CRP),D-二次体以及组织因子 (TF) 和TF途径抑制剂 (TFPI) 等凝血因子.
主要成果:
- 心脏应激标志物 (cTn,CRP) 和凝血因子 (TF,TFPI,D-二次体) 在运动后显著变化.
- 升高的cTn和CRP表示心脏应激.
- 虽然TF和TFPI水平波动,但整体TF:TFPI比率和D-二次体表明血栓形成风险没有净增加.
- 大脑尿素 (BNP) 水平保持不变.
结论:
- 高容量耐力骑自行车会诱导暂时的心脏应激,并改变休骑自行车者的凝血参数.
- 尽管观察到凝血和纤维溶解活性的变化,但血栓形成的风险似乎没有增加.
- 充足的水分和休息是减轻与强烈耐力运动相关的潜在风险的关键.
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