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手术前抑郁症和代谢和减肥手术后的结果:一个系统的叙事审查
Calvin Diep1,2, Sandra Lee3, Yuanxin Xue3
1Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Canada.
概括
手术前的抑郁会影响代谢和减肥手术 (MBS) 的结果. 虽然其对减肥的影响尚不清楚,但有证据表明,它可能会恶化生活质量并增加并发症.
科学领域:
- 腹部外科手术的结果
- 在外科手术中的心理健康.
- 临床研究综合研究
背景情况:
- 在代谢和腹部外科手术 (MBS) 患者中,术前抑郁是常见的.
- 它代表了手术成功的潜在可修改的风险因素.
- 手术前抑郁症对MBS结果的具体影响需要进行系统审查.
研究的目的:
- 系统地审查现有的关于手术前抑郁症和MBS后结果之间的关联的文献.
- 综合有关减肥,生活质量,疼痛和并发症的发现.
- 评估这些关联的证据的确定性.
主要方法:
- 在MEDLINE,Embase,Cochrane和PsychINFO (开始至2023年6月) 的综合文献搜索.
- 包括18项研究 (5项前性,13项后性),涉及5933名接受MBS的参与者.
- 由于异质性,对发现的叙述和表格综合;没有进行元分析.
主要成果:
- 在13项研究中,术前抑郁和减肥结果 (6-72个月) 之间的混合关联.
- 一部分研究表明,术前抑郁症与生活质量下降,急性疼痛增加和更多的术后并发症有关.
- 大多数纳入的研究都显示出高偏差风险,导致证据的确定性低或非常低.
结论:
- 手术前抑郁症对MBS后减肥的影响仍然不确定.
- 新出现的证据表明,手术前抑郁症会对其他以患者为中心的结果产生负面影响.
- 需要进一步的高质量,充足的研究来澄清这些关联.
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