孕产妇艾滋病毒感染对围产期结局的影响:系统性审查
Inioluwa Atowoju1, Prachi Dawer2, Manisha Asrani3
1Department of Obstetrics and Gynecology, Kharkiv National Medical University, Kharkiv, Ukraine.
概括
母亲艾滋病毒感染增加了早产,低出生体重和妊娠年龄婴儿小的风险. 早期干预和改善产前护理对于艾滋病毒感染的孕妇至关重要.
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 围产儿医学 围产儿医学
背景情况:
- 母体人类免疫缺陷病毒 (HIV) 感染带来了全球健康挑战,影响了围产期的结果.
- 早期干预对于改善艾滋病毒感染的母亲和婴儿的产前和产后健康至关重要.
研究的目的:
- 进行对孕妇艾滋病毒感染并发症妊娠中产周期结局的综合分析.
- 基于现有文献,评估艾滋病毒感染对围产期健康的不良影响.
主要方法:
- 在PubMed,MEDLINE和谷歌学者 (2013-2023) 中进行了系统的文献搜索.
- 包括的研究是原始的,观察性的,并专注于母体艾滋病毒感染的围产期结局.
- 数据收集和质量评估遵循了PRISMA指南.
主要成果:
- 分析了来自全球不同地区的9项研究.
- 孕产妇艾滋病毒感染与早产风险增加有关 (OR 1.57),低出生体重 (OR 1.33) 和对妊娠年龄来说小 (OR 1.38).
- 抗逆转录病毒治疗 (ART) 的影响有所不同,但艾滋病毒仍然是收入水平的风险因素.
结论:
- 孕产妇艾滋病毒感染始终与不良围产期结局有关.
- 对于艾滋病毒感染的孕妇,有必要进行有针对性的干预和加强产前护理.
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