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Updated: May 6, 2026

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在肌肉侵入性泌尿器膀癌的器官保存

Scot A Niglio¹, Juhi M Purswani², Peter B Schiff²

¹Department of Hematology and Medical Oncology, Perlmutter Cancer at NYU Langone Health, New York, New York.

Current opinion in oncology

|April 4, 2024

概括

激进囊切除术是肌肉侵入性膀癌 (MIBC) 的标准,但膀保护策略,如三模式疗法 (TMT),显示了类似的结果. 结合辐射,化疗和免疫疗法的新方法为囊切除提供了有前途的替代方案.

科学领域:

在瘤学瘤学.
泌尿器科泌尿器科泌尿器科泌尿器科

背景情况:

肌肉侵入性膀癌 (MIBC) 通常需要激进囊切除术,这是一种与显著的发病率和死亡率风险相关的程序.
器官保存策略旨在管理局部瘤并预防远程转移,改善患者的生活质量.

结论:

MIBC是侵略性的,尽管目前的治疗方法如新辅助化疗和囊切除术,但系统性进展的风险很高.
膀保护选择正在通过新的治疗组合和个性化方法推进.
进一步开发TMT,基于RT的组合和生物标志物驱动的策略对于改善MIBC管理至关重要.

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