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Updated: Jun 29, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

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针对前列腺癌中的雄激素生物合成:对内分泌生理学的影响

Ghazal Kango1,2, Rana Malek2,3, Heather Mannuel1,2,4

  • 1University of Maryland Greenebaum Comprehensive Cancer Center.

Current opinion in oncology
|April 4, 2024
PubMed
概括

向像CYP17A1和CYP11A1这样的雄激素生物合成酶显示出前列腺癌治疗的前景. 然而,这些疗法可能会引起全身副作用,需要仔细的患者管理.

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Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses08:36

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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients12:13

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Testosterone: Functions and Regulation

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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