不同的观点:探索圣乔治呼吸问卷和系统性硬化症相关的间歇性肺部疾病的结果措施之间的关系
Enes Basaran1, Duygu Temiz Karadag2, Ozgur Cakir3
1Division of Rheumatology, Department of Internal Medicine, Kocaeli University Faculty of Medicine, İzmit, Kocaeli, Turkey. enesbasaran90@gmail.com.
Clinical rheumatology
|April 4, 2024
概括
患者报告的结果措施,如圣乔治呼吸问卷 (SGRQ),与系统性硬化症相关的间歇性肺病 (SSc-ILD) 的其他评估有着多种相关性. 建议采用使用互补工具的综合方法进行全面的患者评估.
科学领域:
- 风湿病学和肺部病学
- 临床结果评估的临床结果评估.
- 系统性硬化症研究研究
背景情况:
- 患者报告的结果措施 (PROMs) 评估疾病对日常生活的影响,但它们与系统性硬化症相关的间歇性肺病 (SSc-ILD) 的一致性仍在争论中.
- 圣乔治呼吸道问卷 (SGRQ) 是一个关键的PROM,但它与SSc-ILD中的其他临床,功能和放射性参数的对齐需要澄清.
- 现实世界的数据对于理解PROM在管理SSc-ILD中的实用性至关重要.
研究的目的:
- 调查圣乔治呼吸问卷 (SGRQ) 与SSc-ILD患者的各种结果措施之间的关联.
- 评估SGRQ与功能测试,X光学发现和其他患者报告的结果在现实环境中的一致性.
- 确定PROM与SSc-ILD中的放射性和功能性结果测量的适当性和相互关系.
主要方法:
- 从专门的队列中连续招募SSc-ILD患者.
- 同时使用SGRQ,硬质皮炎健康评估问卷 (sHAQ),呼吸视觉模拟量表 (R-VAS),肺功能测试 (PFT) 和6分钟步行测试 (6-MWT).
- 使用高分辨率计算机断层扫描 (HRCT) 量化肺纤维化程度,并分析SGRQ和其他措施之间的相关性.
主要成果:
- 总SGRQ得分与强迫生命能力 (FVC) 和R-VAS相关. 症状得分与ILD程度相关;活动得分与FVC和R-VAS相关;影响得分与R-VAS相关.
- 在患有 >20%纤维化的患者中,SGRQ总得分与sHAQ和R-VAS相关;活动得分与R-VAS相关;影响得分与6-MWT和R-VAS相关.
- 在SGRQ的症状和活动得分显示,高准确度 (AUC>0.79) 在识别患者>20%的ILD程度和FVC<70%.
结论:
- 圣乔治呼吸道问卷 (SGRQ) 显示了SSc-ILD中不同结果指标的可变相关性.
- 不完整的调整需要采取综合性方法,使用SGRQ与补充性临床,功能和放射性评估一起.
- PROM提供了有价值的主观见解,但它们在SSc-ILD中的解释应该考虑客观措施,以获得整体的患者观点.
相关概念视频
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Physical Assessment of the Respiratory Tract II: Inspection
286
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
Chest Configuration
The chest configuration...
286
Assessment of Respiration
1.1K
The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
1.1K
Physical Assessment of the Respiratory Tract I: Health History
215
Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
215
Respiratory Volumes
1.5K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
1.5K
Assessment of Airway, Skin Color, and Use of Accessory Muscles
998
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
998


