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EMinsight:用于捕捉冷EM显微镜配置和实验结果的工具,用于分析和沉积

Daniel Hatton1, Jaehoon Cha2, Stephen Riggs1

  • 1Data Analysis, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.

Acta crystallographica. Section D, Structural biology
|April 4, 2024
PubMed
概括

低温电子显微镜 (cryoEM) 单粒子分析 (SPA) 正在成为标准. 一个名为EMinsight的新工具捕获元数据,以优化显微镜的使用,并帮助用于结构生物学研究的数据存档.

关键词:
欧盟监督监督是什么意思冰冷化EMEM可以使用.数据挖掘是数据挖掘的一个方法.存款方式 存款方式 存款方式机器学习是机器学习.

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相关概念视频

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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