区域病变及其与主角关闭疾病的关系:一篇评论
1Shantou University Medical College, Shantou, Guangdong, China.
Journal of glaucoma
|April 4, 2024
概括
影响眼镜支纤维的状况 - - 区域病变 - - 在初级角关闭性疾病 (PACD) 患者中很常见,并有助于青光眼的发展. 了解区域病变有助于诊断和治疗PACD.
科学领域:
- 眼科医生 眼科 眼科
- 人体解剖学 解剖学 解剖学
- 病理学 病理学 病理学
背景情况:
- 主要角闭眼光眼 (PACG) 涉及到增加镜头圆顶 (LV) 和镜头厚度 (LT).
- 带膜病变,因带膜松和损失而表现为异常的透镜位置,是PACG的一个关键因素.
- 灵长类眼睛中存在着明显的区域纤维集,影响镜头的位置和形状.
研究的目的:
- 讨论负责镜头中心的区域纤维的解剖特征.
- 总结一下区域病变和初级角关闭疾病 (PACD) 之间的关系.
主要方法:
- 区域病变的诊断包括裂口灯,视镜,超声波生物显微镜 (UBM) 和前段光学连贯断层扫描 (AS-OCT).
- 术内症状可以改善区域病变的诊断.
- 与一般人群相比,PACD患者中 zonulopathy 的患病率很高.
主要成果:
- 区域病变导致更厚,前置的透镜,导致狭窄的角度和升高的眼内压力 (IOP).
- 升高的内压力可以进一步损害区域纤维,加剧角度闭合.
- 玻璃体区域的损失可能会导致前额体旋转,将虹膜拉向前方,从而导致 iridotrabecular 接触.
结论:
- 区域病变是PACD的一个重要危险因素.
- 长前镜片区域 (LAZ) 与视障,短轴长,增加LT,前镜片位置和高原虹膜配置有关,所有这些都是关闭角度的风险因素.
- 对于诊断和治疗来说,全面了解区域病变及其与PACD的联系至关重要.
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