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Updated: Jun 29, 2025

Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
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保存的条状内置维护了运动功能,尽管严重损失了尼格拉尔多巴胺基神经元

Thomas Paß1, Konrad M Ricke1, Pierre Hofmann1

  • 1Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.

Brain : a journal of neurology
|April 4, 2024
PubMed
概括

线粒体DNA突变在多巴氨基神经元中加速,导致帕金森病模型中的细胞死亡. 幸存的神经元补偿,保持运动功能,尽管显著的神经元损失.

关键词:
帕金森病是帕金森氏症的一种疾病.轴突生长的芽 轴突生长的芽多巴胺类神经元的神经元线粒体DNA是线粒体DNA的组成部分.运动症状 运动症状神经退行症的神经退行症

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