血小板衍生的TGF-β1诱导了神经质衍生的抑制细胞在免疫性血小板缺血症中的功能重编程

Lingjun Wang1, Haoyi Wang1, Mingfang Zhu1

  • 1Department of Hematology, Qilu Hospital of Shandong University, Shandong University, Jinan, China.

Blood
|April 4, 2024
PubMed
概括

血小板转化生长因子β1 (TGF-β1) 通过TGF-β/Smad通路扩大髓质衍生抑制细胞 (MDSCs),增强免疫血小板缩 (ITP) 时的免疫平衡. 这种血小板恢复是长期治疗成功的关键.

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