心血管疾病与老年人认知表现的关联
Dae Yong Park1, Yasser Jamil2, Golsa Babapour3
1Department of Medicine, Cook County Health, Chicago, IL.
American heart journal
|April 4, 2024
概括
心血管疾病 (CVD) 与老年人的认知功能下降有关. 充血性心力衰竭和晚年 (≥80) 显著影响认知表现,特别是在数字符号替代测试 (DSST) 中.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 神经科学是一个神经科学.
背景情况:
- 认知功能和心血管疾病 (CVD) 之间的关系是双向的.
- 关于特定心血管疾病亚型和衰老对认知的影响的研究仍然有限.
研究的目的:
- 研究各种心血管疾病 (CVD) 亚型与老年人认知表现之间的关联.
- 检查年龄和特定的心血管疾病条件如何影响认知功能.
主要方法:
- 利用了来自国家健康和营养检查调查 (2011-2014) 的数据,针对60岁以上的成年人.
- 使用CERAD-IR,CERAD-DR,动物流利性测试和数字符号替代测试 (DSST) 在患有和没有心血管疾病的人群中评估认知功能.
- 在不同心血管疾病亚型和年龄组 (≥60岁和≥80岁) 的认知分数进行比较.
主要成果:
- 与没有心血管疾病的老年人相比,在所有认知测试中,患有心血管疾病的老年人表现较低.
- 经过调整后,只有数字符号替代试验 (DSST) 的得分在患有心血管疾病的老年人中仍然明显较低.
- 充血性心力衰竭 (CHF) 和处于最古老的队列 (≥80岁) 与较差的DSST和动物流利性测试表现有关.
结论:
- 患有心血管疾病 (CVD) 的老年人表现出认知能力下降.
- 认知缺陷在患有充血性心力衰竭 (CHF) 的老年人和患有心血管疾病的80岁及以上的人群中更为明显.
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