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抗生素管理干预在门诊机构的尿路感染:一个叙事审查
Larissa Grigoryan1, Barbara W Trautner2
1Department of Family and Community Medicine, Baylor College of Medicine, 3701 Kirby Drive, Suite 600, Houston TX 77098, USA; Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
在门诊泌尿道感染 (UTI) 中选择错误的抗生素或持续时间会导致过度使用抗生素. 未来对尿路感染的抗生素管理研究必须评估治疗有效性和实施成功.
科学领域:
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
- 公共卫生 公共卫生
背景情况:
- 门诊泌尿道感染 (UTI) 的抗生素选择和持续时间不恰当,普遍存在,大大导致抗菌素耐药性.
- 关于尿路感染抗生素管理的现有研究通常采用前后设计,涉及多方面的干预措施,通常显示抗生素使用的适当性得到改善.
- 审计和反是这些干预中常见但潜在的不可持续的策略.
研究的目的:
- 要突出在门诊性尿路感染中不适当使用抗生素的常见问题.
- 审查现有的门诊尿路感染抗生素管理研究方法.
- 建议未来的研究方向,重点关注有效性和实施.
主要方法:
- 审查现有关于尿路感染门诊抗生素管理的研究.
- 对干预策略的分析,特别是审计和反.
- 确定常见的研究设计 (前后,多方面的干预).
主要成果:
- 门诊性尿路感染抗生素管理试验中的多方面的干预措施通常改善了抗生素处方的适当性.
- 审计和反,虽然经常使用,但可能缺乏长期可持续性作为一个独立的战略.
- 目前的研究往往侧重于有效性,不太重视实施成功.
结论:
- 在门诊性尿道感染中解决不适当的抗生素使用对于打击过度使用抗生素至关重要.
- 未来的研究应该优先评估抗生素管理干预措施对尿路感染的临床有效性和实际实施.
- 改善门诊处方抗生素的可持续策略需要进一步研究.
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