拔牙后替代牙科阿片类药物处方的替代方案 (ADOPT):一个阶梯集群随机试验的协议
Douglas R Oyler1, Philip M Westgate2, Sharon L Walsh3
1Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, 760 Press Avenue, Ste. 260, Lexington, KY, 40536, USA. doug.oyler@uky.edu.
BMC oral health
|April 4, 2024
概括
牙医可以通过使用行为干预来减少青少年和年轻人的阿片类药物处方 (AYA). 这项研究表明,多组件干预有效地改变了牙科处方习惯,减少了提取后的阿片类药物使用.
科学领域:
- 牙科手术 牙科手术
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 青少年和年轻人 (AYA) 在牙科手术后面有问题阿片类药物使用的高风险.
- 牙医和口腔外科医生是阿片类药物治疗AYA的重要处方者,主要是在拔牙后.
- 非阿片类药物止痛药提供可比的缓解疼痛,并由专业组织推.
研究的目的:
- 评估多组分行为干预在改变牙医和口腔外科医生的阿片类药物处方行为的有效性.
- 为了减少青少年和年轻成年人 (AYA) 接受牙拔牙的阿片类药物处方.
主要方法:
- 一个多站点阶段子集群随机试验,涉及12个临床实践中多达33名牙科提供者.
- 干预包括处方者教育和提供非阿片类止痛药 (乙氨基和布洛芬) 与标准化的患者说明.
- 主要结局:患者级电子提取后阿片类药物处方. 二次结果:实施,疼痛控制和患者满意度.
主要成果:
- 这项研究被注册为NCT06275191.1.
- 主要分析将使用通用估计方程将干预和通常护理组之间的阿片类药物处方率进行比较.
- 二次分析将检查提供者的看法和患者报告的结果.
结论:
- 这项现实研究解决了理解修改牙科处方的干预措施的关键需求.
- 研究结果将为减少青少年和年轻人阿片类药物处方 (AYA) 的策略提供信息.
- 多组件干预措施在修改牙科处方行为方面显示出前景.
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