口服运动后大提取物补充剂增强了糖原的补充,但并没有对人类运动的骨肌肉中线粒体生物发生的mRNA表达进行上调
I-Shiung Cheng1, Jung-Piao Tsao2, Jeffrey R Bernard3
1National Taichung University of Education, Department of Physical Education, Taichung City, Taiwan.
Journal of the International Society of Sports Nutrition
|April 5, 2024
概括
急性大提取物 (GA) 补充剂增强了运动后的肌肉糖原补充. 然而,它没有影响骨肌肉中的葡萄糖吸收或线粒体基因表达.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 分子生物学分子生物学
背景情况:
- 大提取物 (GA) 被认为具有潜在的抗氧化,抗炎和葡萄糖调节性质.
- 研究运动后的营养策略对于优化肌肉恢复和适应至关重要.
研究的目的:
- 检查运动后GA补充对GLUT4表达,糖原补充和线粒体生物合成相关的转录因子在人类骨肌肉中的影响.
主要方法:
- 这是一项单盲,交叉,平衡研究,涉及12名参与者.
- 参与者在运动后接受了2000毫克GA或安慰剂,并吃了一顿高血糖碳水化合物餐.
- 肌肉活检和血液样本被分析为糖原,GLUT4,转录因子和代谢标志物.
主要成果:
- 与安慰剂相比,GA的骨肌肉糖原补充量明显高于安慰剂.
- 两组之间没有观察到GLUT4蛋白表达的显著差异.
- 在GA和安慰剂组中,PGC1-α基因表达增加;GA增强了TFAM和FIS1.
结论:
- 运动后急性GA补充剂可能会增强肌肉糖原复合.
- 观察到的糖原补充似乎独立于葡萄糖吸收或线粒体基因表达途径的变化.
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