在生育年龄明显正常的妇女中,感知压力与甲状腺功能之间的关系的横截面研究
Sandhya H Puttaswamy1, Neeta P Nandibewur2, Pawan Kumar1
1Department of Physiology, Vijayanagar Institute of Medical Sciences, Ballari, IND.
Cureus
|April 5, 2024
概括
女性的高压力可能会影响甲状腺功能,可能会增加甲状腺刺激激素 (TSH) 水平. 年龄,BMI和婚姻持续时间等因素与亚临床甲状腺功能低下症 (SCH) 有关.
科学领域:
- 内分泌学 在内分泌学.
- 妇女健康 妇女健康
- 心理神经免疫学 心理神经免疫学
背景情况:
- 印度妇女报告了高压力和缺乏放松时间,特别是那些处于生殖年龄的妇女.
- 慢性压力是发展自身免疫性疾病的已知危险因素,包括甲状腺功能障碍.
研究的目的:
- 在生育年龄的健康女性中,研究感知压力和甲状腺功能参数之间的关联.
- 为了确定与甲状腺功能障碍相关的人口和生活方式因素.
主要方法:
- 一项涉及114名工作女性 (年龄在20-49岁) 的横截面研究,没有先前的病史或甲状腺病史.
- 使用感知应激量表 (PSS) 和甲状腺功能 (TSH,T3,T4) 通过电化学发光免疫测试来评估感知应激.
- 收集人体测量 (年龄,BMI) 和临床数据,包括婚姻状况,婚姻持续时间和月经周期阶段.
主要成果:
- 在感知压力 (PSS) 和甲状腺刺激激素 (TSH) 水平 (r=0.060) 之间发现了一个非显著的正相关性.
- 亚临床甲状腺功能低下症 (SCH) 被定义为TSH>4.2 IU/L;与甲状腺功能正常的人相比,患有SCH的参与者在年龄,BMI和婚姻持续时间方面表现出显著差异.
- 在正常甲状腺功能和SCH的女性之间没有观察到PSS得分的显著差异.
结论:
- 虽然感知压力与TSH在这个队列中没有显著的相关性,但趋势表明存在潜在的联系.
- 年龄较大,BMI较高和婚姻持续时间较长与亚临床甲状腺功能低下症的风险增加有关.
- 常规的甲状腺功能监测和压力管理建议在生育年龄的妇女经历高压力.
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