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乳头病变发生在长期存在的状斑块内,皮肤颜色为菲茨帕特里克4-5型
Joelle Teoh1, Alex Gan1, Joshua Ramalingam1
1Nottingham University Hospitals NHS Trust Nottingham UK.
Skin health and disease
|April 5, 2024
概括
基底细胞癌 (BCC) 可以发生在脂质癌 (SN) 中,甚至在具有较深色皮肤类型的个体中 (菲茨帕特里克 4-5). 这一案例突显了头皮脂质内BCC的发展,强调了不同人群中的风险.
科学领域:
- 皮肤病学和瘤学:专注于皮肤瘤及其在先前存在的良性形中发生的情况.
背景情况:
- 油脂性纳维 (SN),在头皮上常见的良性牙瘤,可以发展出各种瘤.
- 在SN中恶性转变很少见 (2.5%),基底细胞癌 (BCC) 是最常见的 (0.8%).
- 虽然BCC风险在较暗的皮肤类型中通常较低 (Fitzpatrick 4-5),但它并不缺席.
研究的目的:
- 报告发生在头皮上的脂质 (SN) 内发生的基底细胞癌 (BCC) 病例.
- 为了强调BCC可以发生在肤色较深的人身上 (菲茨帕特里克皮肤类型4-5),挑战对较低风险的看法.
- 提高皮肤颜色患者在SN内BCC发育的认识.
主要方法:
- 一份病例报告详细介绍了一名23岁的男性,他的头皮上已经存在的状斑块上有一个深色素的乳头病变.
- 临床检查,皮肤镜检查,皮病变的穿孔切除活检,以及基础斑块的完全切除.
- 两种病变的组织病理学分析,以确定生长的性质.
主要成果:
- 组织病理学证实基底细胞癌 (BCC) 发生在头皮上的脂质 (SN).
- 患者患有菲茨帕特里克皮肤4-5型,表明皮肤色调较深.
- 底部斑块显示出与成熟的脂质相一致的特征,包括脂质腺,缺陷的毛囊和乳头瘤.
结论:
- 基底细胞癌 (BCC) 可以在皮肤类型为4-5的菲茨帕特里克皮肤类型患者的脂质性肌肉 (SN) 中发展.
- 这一案例强调,肤色有色的个体并非免于在脂质海维菌中发展BCC.
- 需要提高警和意识,以检测所有皮肤类型的脂质肌肉中的BCC.
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