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Updated: Jun 29, 2025

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功能突变的RAD51分离使复制叉维护失效,但保留了DSB修复

Mi Young Son1, Ondrej Belan2, Mario Spirek2,3

  • 1Department of Molecular Medicine, The Barshop Institute for Longevity and Aging Studies, The Cancer Therapy Research Center, UT Health San Antonio, San Antonio, TX 78229, USA.

iScience
|April 5, 2024
PubMed
概括

一种特定的RAD51突变会损害复制叉的保护,但不会损害双链断裂的修复,这揭示了RAD51线丝稳定在DNA修复途径中的独特作用.

关键词:
遗传学 是一个遗传学.分子生物学分子生物学分子相互作用分子相互作用.生物分子的特性

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