肥胖:对心血管和脑血管疾病的影响
Savi Dutta1, A K Singhal1,2, Varsha Suryan1,3
1Department of Biochemistry, Shree Guru Gobind Singh Tricentenary University, Gurugram, Haryana 122505 India.
肥胖会导致代谢综合征,包括胰岛素抵抗和高胆固醇,增加动脉样硬化,心脏病发作和中风的风险. 持续的肥胖会显著提高这些心血管和脑血管疾病的风险.
科学领域:
- 心血管科学 心血管科学
- 代谢健康 代谢健康
- 肥胖问题研究研究
背景情况:
- 肥胖是一种复杂的疾病,与代谢综合征的发展有关.
- 代谢综合征的组成部分,如胰岛素抵抗,失脂症和高血压与血管动脉样硬化有关.
- 动脉样硬化是心血管和脑血管疾病的基础.
研究的目的:
- 为了将肥胖与代谢综合征参数相关联.
- 调查肥胖,动脉样硬化和心血管/脑血管疾病之间的联系.
- 审查与肥胖有关的心血管和脑血管事件的发病性.
主要方法:
- 使用MEDLINE,Scopus,PubMed和谷歌学者进行全面的在线文献调查.
- 从1970年到2023年搜索相关期刊.
- 关键搜索词包括"肥胖"",瘦素"",2型糖尿病"",动脉样硬化"",心血管和脑血管疾病".
主要成果:
- 肥胖的超瘦血症可以诱发高血糖症,导致高胆固醇血症.
- 持续的高胆固醇血会促进动脉样硬化.
- 肥胖会引发高血糖,高胆固醇和动脉动脉生成,增加心脏病发作和中风的风险.
结论:
- 与肥胖相关的并发症通常始于勒素和胰岛素抵抗.
- 肥胖的代谢不规则会导致心脏病发作和中风的发生.
- 动脉样硬化相关的心血管和脑血管事件是肥胖个体的独立风险.
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