对实验室性能进行评估,考虑分析前和分析后的质量指标
Disha Gajjar1, Ashishkumar Agravatt1, Asha Khubchandani1
1BJ Medical College and Civil Hospital, Ahmadabad, Gujarat India.
Indian journal of clinical biochemistry : IJCB
|April 5, 2024
概括
质量指标 (QI) 对实验室的性能至关重要. 这项研究发现,虽然样本体积不足等分析前错误很常见,但随着时间的推移,它们会减少,分析后错误在可接受的范围内.
科学领域:
- 临床生物化学 临床生物化学
- 实验室医学 实验室医学
- 医疗保健中的质量管理
背景情况:
- 质量指标 (QI) 对于评估实验室性能和改善整个测试过程至关重要.
- 非分析阶段 (分析前和分析后) 显著影响实验室服务质量和临床决策.
- 评估非分析性QI对于提高实验室整体质量至关重要.
研究的目的:
- 在NABL认可的临床生物化学实验室评估和审查非分析性质量指标.
- 在大型实验室环境中识别和量化分析前和分析后的错误.
- 评估错误率的趋势及其对实验室性能的影响.
主要方法:
- 在2018年1月至2021年12月期间处理的1,439,011个样本的回顾性研究.
- 评估七个QI:QI-8 (不合适的样品),QI-9 (不合适的容器),QI-10 (血液溶解),QI-12 (不充分的体积),QI-15 (不匹配的样品),QI-21 (周转时间) 和QI-22 (关键值).
- 分析基于国际临床化学联合会的质量规范.
主要成果:
- 总预分析错误:3.72% (53,669个样本),样本体积不足是最常见的 (2.37%).
- 样本体积不足,血液溶解和不匹配样本的错误率显示,逐年逐渐下降.
- 分析后的误差为1.32% (19,002个样本),周转时间异常值和关键值通信在可接受的范围内.
结论:
- 分析之外的QI是监测实验室过程性能的有效工具.
- 虽然预分析错误需要干预,但它们的下降趋势表明质量改进工作取得了成功.
- 持续监测,员工培训和认证文件的传播是维持和加强实验室服务和患者护理所必需的.
相关概念视频
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Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
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01:15Data Validation
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01:16Contaminants and Errors
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Effective sample preparation is crucial for accurate and reliable laboratory analysis. During this process, two significant sources of error can arise: concentration bias from improper sample splitting and contamination caused by methods used to reduce particle size, such as grinding or homogenization. Identifying and minimizing these potential errors is crucial to ensuring the validity of the analysis.
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